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Survival differences of patients with ureteral versus pelvicalyceal tumours: a systematic review and meta-analysis.
- Source :
- Archives of Medical Science; 2021, Vol. 17 Issue 3, p603-612, 10p
- Publication Year :
- 2021
-
Abstract
- <bold>Introduction: </bold>Worse survival in upper tract urothelial carcinoma (UTUC) in the presence of a tumour in the ureter vs. pelvicalyceal tumours is reported in some studies; however, the definition of ureteral involvement (UI) varies across studies. We systematically evaluated evidence regarding the prognostic role of UI in overall and cancer-specific survival of patients with UTUC.<bold>Material and Methods: </bold>A systematic search of PubMed, Scopus and Web of Knowledge was performed in March 2018.<bold>Results: </bold>The results were presented as a comparison between ureteral vs. pelvicalyceal tumours. A total of 14,895 patients were identified. Cumulative analyses indicated that UI worsens cancer-specific survival (CSS) and overall survival (OS), with a pooled HR of 1.52 (p < 0.001) and 1.39 (p = 0.004), respectively.<bold>Conclusions: </bold>Our meta-analysis identified UI in UTUC as an adverse prognostic factor. [ABSTRACT FROM AUTHOR]
- Subjects :
- TUMORS
TRANSITIONAL cell carcinoma
PROGNOSIS
Subjects
Details
- Language :
- English
- ISSN :
- 17341922
- Volume :
- 17
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Archives of Medical Science
- Publication Type :
- Academic Journal
- Accession number :
- 150114482
- Full Text :
- https://doi.org/10.5114/aoms.2019.89893