A microbiota‐based predictive model for type 2 diabetes remission induced by dietary intervention: From the CORDIOPREV study.

Dear Editor, Type 2 diabetes is widely considered as a chronic, progressive disease that is a consequence of the seemingly inexorable decline in -cell function.1 However, recent studies have demonstrated that in the early stages of development, it may be reversible. We evaluated the probability of type 2 diabetes remission by COX regressions of the score generated by categorizing patients into (ascending) tertiles of the microbiome-based response prediction score value (Figure 3A). A microbiota-based predictive model for type 2 diabetes remission induced by dietary intervention: From the CORDIOPREV study In conclusion, our results suggest that there is a gut microbiota profile associated with type 2 diabetes remission and provide compelling evidence of a potential role of the microbiome as a predictive factor for responders to diet-induced type 2 diabetes remission in newly diagnosed patients with CHD. [Extracted from the article]