Hematological Parameters Characteristics in Children with Obstructive Sleep Apnea with Obesity.

The results suggested that obesity may aggravate the inflammatory status in the body of children on the basis of OSA, which was undoubtedly a further impact on systematic inflammation, namely, obesity could amplify the short-term and long-term damage of OSA. Keywords: obstructive sleep apnea, obesity, propensity score matching, hematological parameter, inflammation, hypercoagulation Introduction Obstructive sleep apnea (OSA) is a condition secondary to partial or complete obstruction of upper airway during sleep. 8 Notwithstanding previous mentioned studies have described the relationship between OSA and inflammation, obesity and inflammation, respectively, 2,9 few studies focus on the inflammatory status in children affected with both OSA and obesity. 24,28,39 In our study, obvious results were observed that the levels of WBC, NEUT, NLR, FIB in the obese children with OSA were significantly higher than those in the normal weight children with OSA, while the level of APTT in the obese children with OSA was lower than that in the normal weight children with OSA. [Extracted from the article]