Bisphenol A and S in the Urine of Newborns: Plastic for Non-Food Use Still without Rules.

Simple Summary: The aim of our study was to assess the effects of Bisphenols exposure on pregnancy and neonatal life. In this optic, we have: (a) determined Bisphenols concentration levels (Bisphenol A and Bisphenol S) in a group of newborns and their mothers, (b) identified factors, habits and devices possibly responsible for Bisphenols uptake, and (c) determined some possible health effect of Bipshenols exposure. The statistical analyses showed no significant correlations between maternal and neonatal Bisphenols concentration levels. In newborns, on the contrary, a positive correlation between pacifier use and Bisphenol S total and free concentration was detected. Beside, a significant correlation was also found between oral glucose administration and concentration levels of free Bisphenols A. Our study points to a central role of lifestyle, hospital procedures and neonatal devices in inducing Bisphenols exposure during perinatal period. This is the first report of Bisphenols contamination in newborns due to widely non-alimentary products destined for newborn care (glucose solution containers for Bisphenol A and the pacifiers for the Bisphenol S). Further studies are advocated to clarify both the impact of such other Bisphenols forms on human health and the potential Bisphenol A exposure sources during neonatal and childhood life. The aim of the present study was to assess the effects of bisphenol (BP) exposure on pregnancy and neonatal life. We have (a) determined BP (BPA and BPS) concentration levels in a group of newborns and their mothers; (b) identified factors, habits, and devices possibly responsible for BP uptake; and (c) determined the effect of BP exposure. No significant correlations were detected between maternal and neonatal BP concentration levels. In newborns, positive correlations between pacifier use and BPS total (p = 0.04) and free BPS (p = 0.03) concentrations were detected. A significant correlation was also found between oral glucose administration and concentration levels of free BPA (p < 0.05). Our study points to a central role of lifestyle, hospital procedures, and neonatal devices in inducing BP exposure, especially during the perinatal period. This is the first report of BP contamination in newborns due to widely non-alimentary products designed for newborn care, such as glucose-solution containers for BPA and pacifiers for BPS. Further studies are advocated in order to clarify both the impact of other BP forms on human health and development, as well as potential BPA exposure sources during neonatal and childhood life. [ABSTRACT FROM AUTHOR]