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Lung biopsy in children: when is it useful?
- Source :
- Archives of Disease in Childhood; Mar2021, Vol. 106 Issue 3, p291-293, 3p
- Publication Year :
- 2021
-
Abstract
- <bold>Aim: </bold>To provide a further insight into the usefulness of lung biopsy in children.<bold>Methods: </bold>Lung biopsies in children from January 2007 to December 2017 were reviewed (n=39). The histology results were categorised as: definitive diagnosis, normal lung parenchyma, inconclusive.<bold>Results: </bold>Lung biopsy provided a definitive diagnosis in 25 (64%) cases. A suspected diagnosis was confirmed in 16 (41%) and a new diagnosis was found in 9 (23%) children. Histology was inconclusive in 11 (28%) cases and normal in 3 (8%). Fifteen (38%) children had treatment altered due to the biopsy result.<bold>Conclusion: </bold>Lung biopsy mostly confirmed the suspected diagnosis and was associated with a low procedure related morbidity (n=1) and mortality (n=0). Importantly, the biopsy result identified a pathology which altered treatment in over one third of patients. However, in a number of cases the histology was inconclusive, therefore careful patient selection is recommended to maximise diagnostic yield. [ABSTRACT FROM AUTHOR]
- Subjects :
- INTERSTITIAL lung diseases
CA 125 test
LUNGS
BIOPSY
GRAFT versus host disease
Subjects
Details
- Language :
- English
- ISSN :
- 00039888
- Volume :
- 106
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Archives of Disease in Childhood
- Publication Type :
- Academic Journal
- Accession number :
- 149456602
- Full Text :
- https://doi.org/10.1136/archdischild-2019-318443