Low Cycle Threshold Value in Xpert MTB/RIF Assay May Herald False Detection of Tuberculosis and Rifampicin Resistance: A Study of Two Cases.

Authors :: Ngabonziza, Jean Claude S
Decroo, Tom
Maniliho, Rodrigue
Habimana, Yves M
Deun, Armand Van
Jong, Bouke C de
Source :: Open Forum Infectious Diseases; Feb2021, Vol. 8 Issue 2, p1-5, 5p
Publication Year :: 2021
Abstract: We report 2 cases for whom Xpert MTB/RIF falsely signaled rifampicin-resistant tuberculosis, based on unusually low cycle threshold and 3 of 5 probes missing. Other mycobacterial tests were negative. Further optimization of the Xpert MTB/RIF algorithm is warranted. [ABSTRACT FROM AUTHOR]

Subjects :: TUBERCULOSIS
RIFAMPIN
MULTIDRUG-resistant tuberculosis
ALGORITHMS

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