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NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling.
- Source :
- Clinical Case Reports; Mar2021, Vol. 9 Issue 3, p1472-1477, 6p
- Publication Year :
- 2021
-
Abstract
- This is the first report of a NACC2‐NTRK2 fusion in a histological glioblastoma. Oncogenomic analysis revealed this actionable fusion oncogene in a pediatric cerebellar glioblastoma, which would not have been identified through routine diagnostics, demonstrating the value of clinical genome profiling in cancer care. [ABSTRACT FROM AUTHOR]
- Subjects :
- GLIOBLASTOMA multiforme
GENOMES
CANCER treatment
ONCOGENES
Subjects
Details
- Language :
- English
- ISSN :
- 20500904
- Volume :
- 9
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Clinical Case Reports
- Publication Type :
- Academic Journal
- Accession number :
- 149399594
- Full Text :
- https://doi.org/10.1002/ccr3.3804