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Position statement for a pragmatic approach to immunotherapeutics in patients with inflammatory skin diseases during the coronavirus disease 2019 pandemic and beyond.

Authors :
Beecker, J.
Papp, K.A.
Dutz, J.
Vender, R.B.
Gniadecki, R.
Cooper, C.
Gisondi, P.
Gooderham, M.
Hong, C.H.
Kirchhof, M.G.
Lynde, C.W.
Maari, C.
Poulin, Y.
Puig, L.
Source :
Journal of the European Academy of Dermatology & Venereology; Apr2021, Vol. 35 Issue 4, p797-806, 10p
Publication Year :
2021

Abstract

Coronavirus disease 2019 (COVID‐19) is caused by SARS‐CoV‐2, a novel RNA virus that was declared a global pandemic on 11 March 2020. The efficiency of infection with SARS‐CoV‐2 is reflected by its rapid global spread. The SARS‐CoV‐2 pandemic has implications for patients with inflammatory skin diseases on systemic immunotherapy who may be at increased risk of infection or more severe infection. This position paper is a focused examination of current evidence considering the mechanisms of action of immunotherapeutic drugs in relation to immune response to SARS‐CoV‐2. We aim to provide practical guidance for dermatologists managing patients with inflammatory skin conditions on systemic therapies during the current pandemic and beyond. Considering the limited and rapidly evolving evidence, mechanisms of action of therapies, and current knowledge of SARS‐CoV‐2 infection, we propose that systemic immunotherapy can be continued, with special considerations for at risk patients or those presenting with symptoms. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09269959
Volume :
35
Issue :
4
Database :
Complementary Index
Journal :
Journal of the European Academy of Dermatology & Venereology
Publication Type :
Academic Journal
Accession number :
149170371
Full Text :
https://doi.org/10.1111/jdv.17075