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Occupational scleroderma. A 17 -- year follow -- up study.

Authors :
Ishikawa, O.
Warita, S.
Tamura, A.
Miyachi, Y.
Source :
British Journal of Dermatology; Nov1995, Vol. 133 Issue 5, p786-789, 4p
Publication Year :
1995

Abstract

Two patients with a scleroderma-like disorder induced by epoxy resins were reported from the Department of Dermatology, Gunma University School of Medicine, Japan in 1980. Here, we describe the clinical and laboratory characteristics of these patients after 17 years' follow-up from 1976 to 1995. Their systemic manifestations and indurated sclerotic skin changes disappeared within 5 years. No internal organ involvement has developed during the period of follow-up. On routine laboratory tests, no abnormalities have been found in the peripheral blood or in the blood chemistry or serology. Histological examination revealed atrophy of the dermis and restoration of the normal pattern of tine collagen bundles, when compared with the previous skin biopsy specimens. This scleroderma-like disorder induced by epoxy resins is considered to be different from systemic sclerosis: it has an acute onset and a fairly good prognosis, and does not show involvement of the internal organs. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00070963
Volume :
133
Issue :
5
Database :
Complementary Index
Journal :
British Journal of Dermatology
Publication Type :
Academic Journal
Accession number :
14913353