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Effect of Fluoropyrimidines on the Growth of Ureaplasma urealyticum.
- Source :
- Nucleosides, Nucleotides & Nucleic Acids; Aug2004, Vol. 23 Issue 8/9, p1499-1502, 4p, 3 Graphs
- Publication Year :
- 2004
-
Abstract
- In the present study, we investigated the effect of fluoropyrimidines on the growth of Ureaplasma urealyticum. Addition of fluoropyrimidines strongly inhibited bacterial growth. Growth inhibition by these analogues could be reversed by addition of either thymidine or deoxyuridine, suggesting inhibition of thymidylate biosynthesis as the mechanism in operation. [ABSTRACT FROM AUTHOR]
- Subjects :
- FLUOROPYRIMIDINES
NUCLEOSIDES
BACTERIAL growth
THYMIDINE
BIOSYNTHESIS
Subjects
Details
- Language :
- English
- ISSN :
- 15257770
- Volume :
- 23
- Issue :
- 8/9
- Database :
- Complementary Index
- Journal :
- Nucleosides, Nucleotides & Nucleic Acids
- Publication Type :
- Academic Journal
- Accession number :
- 14898176
- Full Text :
- https://doi.org/10.1081/NCN-200027714