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Gene expression profiling predicts relapseāfree and overall survival in newly diagnosed myeloma patients treated with novel therapies.
- Source :
- British Journal of Haematology; Feb2021, Vol. 192 Issue 4, pe115-e120, 6p
- Publication Year :
- 2021
-
Abstract
- Gene expression profiling predicts relapse-free and overall survival in newly diagnosed myeloma patients treated with novel therapies In addition, the LR FISH/HR GEP had a relapse rate at 12 months of 30% (3/12 patients) I versus i 0% in patients with LR GEP/HR FISH (0/8 patients; B Table b IA B ) b . Patients with HR GEP/HR FISH demonstrated reduced RFS and OS when compared to LR GEP/FISH with HR GEP being the best predictor of early RFS. For example, patients with HR GEP had a death rate due to multiple myeloma (MM) of 21% (HR GEP/HR FISH), 25% (HR GEP/LR FISH), 0% (LR GEP/HR FISH) and 6% (LR GEP/LR FISH) ( I P i = 0-03; B Table b IB B ) b . [Extracted from the article]
- Subjects :
- GENE expression profiling
FLUORESCENCE in situ hybridization
Subjects
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 192
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 148722853
- Full Text :
- https://doi.org/10.1111/bjh.17344