Reply to Comment on Failure of a Mexican antivenom on recovery from snakebite-related coagulopathy in French Guiana.

Dear Editor, We thank Drs Greene and Brandehoff for their interest in our article, but we are surprised that they consider a study comparing the kinetics of hemostasis in 84 patients envenomed mainly by I Bothrops atrox i with and without antivenom as "irrelevant" compared to 9 cases taken from a descriptive study without a comparative group. If I B. atrox i injects less venom than I B. asper i , a lower dose of I Antivipmyn Tri SP TM sp i is required. Untreated patients recover from coagulopathy within 14 to 30 h after bite, which is not significantly different from our patients treated with I Antivipmyn Tri SP TM sp i . [Extracted from the article]