Urine Titin N-Fragment as a Biomarker of Muscle Injury for Critical Illness Myopathy.

The article presents the case study on Urine Titin N-Fragment as a Biomarker of Muscle Injury for Critical Illness Myopathy, a part of ICU-acquired weakness, held at Hitachi General Hospital in Japan. Titin extends from Z-disc to M-line and serves as a molecular spring and generating passive stiffness. It also highlights the methods which includes Population and setting, Data collection and evaluation and statistical analysis.