Supramolecular Complex of 20-Hydroxyecdysone-3-acetate with β-Cyclodextrin and Its Biological Activity.

Authors :: Tuleuov, B. I.
Temirgaziev, B. S.
Kozhanova, A. M.
Seydakhmetova, R. B.
Turdybekov, K. M.
Seilkhanov, T. M.
Seilkhanov, O. T.
Drasar, P.
Adekenov, S. M.
Source :: Russian Journal of General Chemistry; 2020, Vol. 90 Issue 12, p2258-2263, 6p
Publication Year :: 2020
Abstract: In order to obtain new potentially bioactive substances and to investigate the effect of bulky functional groups on the formation of supramolecular complexes, 20-hydroxyecdysone triacetate has been synthesized, its spatial structure has been determined, and its complexation with β-cyclodextrin has been studied by means of NMR. The anti-inflammatory activity of the obtained water-soluble complex has been assessed. [ABSTRACT FROM AUTHOR]

Subjects :: CYCLODEXTRIN derivatives
GROUP formation
FUNCTIONAL groups
NUCLEAR magnetic resonance spectroscopy
TRIACETATE

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