Predictive values of D-dimer for adverse pregnancy outcomes: a retrospective study.

Keywords: adverse outcome; D-dimer; prediction; pregnancy; reference interval EN adverse outcome D-dimer prediction pregnancy reference interval e99 e101 3 02/06/21 20210301 NES 210301 To the Editor, Pregnancy is a complicated physiological process, during which the balance of the hemostatic systems is tipped toward a hypercoagulable state [[1]]. Unlike postpartum hemorrhage and preeclampsia, much fewer reports were focused on the associations between D-dimer and preterm birth and fetal distress. Further, the elevation of D-dimer was found to be associated with increased risks of preeclampsia, fetal distress, postpartum hemorrhage and a decreased risk of preterm delivery in our retrospective study. [Extracted from the article]