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Pulmonary function in patients surviving to COVID-19 pneumonia.

Authors :
Fumagalli, Alessia
Misuraca, Clementina
Bianchi, Achille
Borsa, Noemi
Limonta, Simone
Maggiolini, Sveva
Bonardi, Daniela Rita
Corsonello, Andrea
Di Rosa, Mirko
Soraci, Luca
Lattanzio, Fabrizia
Colombo, Daniele
Source :
Infection; 2021, Vol. 49 Issue 1, p153-157, 5p, 1 Chart, 1 Graph
Publication Year :
2021

Abstract

Purpose: The aim of our study was to assess respiratory function at the time of clinical recovery and 6 weeks after discharge in patients surviving to COVID-19 pneumonia. Methods: Our case series consisted of 13 patients with COVID-19 pneumonia. Results: At the time of clinical recovery, FEV1 (2.07 ± 0.72 L) and FVC (2.25 ± 0.86 L) were lower compared to lower limit of normality (LLN) values (2.56 ± 0.53 L, p = 0.004, and 3.31 ± 0.65 L, p < 0.001, respectively), while FEV1/FVC (0.94 ± 0.07) was higher compared to upper limit of normality (ULN) values (0.89 ± 0.01, p = 0.029). After 6 weeks pulmonary function improved but FVC was still lower than ULN (2.87 ± 0.81, p = 0.014). Conclusion: These findings suggest that COVID-19 pneumonia may result in clinically relevant alterations in pulmonary function tests, with a mainly restrictive pattern. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03008126
Volume :
49
Issue :
1
Database :
Complementary Index
Journal :
Infection
Publication Type :
Academic Journal
Accession number :
148427242
Full Text :
https://doi.org/10.1007/s15010-020-01474-9