Histophysiological Considerations Deals Damaging of Rat's Kidney by Examined Doses of Heroin.

Scientific gain after treating about 100lab rats with heroin of several doses to examine the quantitative physical, clinical chemistry and histopathological tests. Accompanied bymodern statistical analysis, the results explain an obvious differentiation (p<0.05) for urine creatinine, serum creatinine, creatinine clearance, 24-hour proteinuria, protein/creatinine ratio and urea; at the same time as other parameters showed slight and concealed splendour achievements results recorded ups or downs reported below for Weight, food intake, water intake and urine volume. Judgment based on reasoning were proving the negative effects of heroin on the kidneys of the lab rats successes an acute damages on the histopathological levels. [ABSTRACT FROM AUTHOR]