Improved resolution and sensitivity of [18F]MFBG PET compared with [123I]MIBG SPECT in a patient with a norepinephrine transporter–expressing tumour.

Improved resolution and sensitivity of [18F]MFBG PET compared with [123I]MIBG SPECT in a patient with a norepinephrine transporter-expressing tumour Moreover, if neural crest tumour patients are considered for peptide receptor radionuclide therapy, addition of norepinephrine transporter imaging to the pre-therapeutic work-up allows evaluating whether [ SP 131 sp I]MIBG or a combination treatment may increase therapeutic efficacy. [ SP 18 sp F]MFBG is a promising clinical PET alternative for [ SP 123 sp I]MIBG, offering improved sensitivity, same-day imaging and the possibility of PET/MR imaging, as a one-stop-shop for patients with norepinephrine transporter-expressing tumours. [Extracted from the article]