The Diagnostic Value of Prostate Targeted Puncture Guided by MRI Combined with Ultrasound Fusion Imaging in Prostate Cancer with PI-RADS Score ≥ 3 Points.

In order to explore the diagnostic value of prostate targeted puncture guided by MRI combined with ultrasound fusion imaging (MR-TRUS) in patients with prostate cancer of PI-RADS score ≥ 3 points, 100 patients who sought medical care in our hospital were enrolled. All of them were performed targeted biopsy via both MR-TRUS guided puncture and traditional puncture. And all the patients were tested the level of prostate specific antigen (PSA). According to 4 < PSA ≤ 10 µ g /L, 10 < PSA ≤ 20 µ g /L, 20 < PSA ≤ 50 µ g/L, and PSA > 50 µ g /L, the MR-TRUS guided puncture group (group A) and the traditional puncture group (group B) were both divided into 4 subgroups. The sensitivity, specificity and accuracy of different puncture methods for the diagnosis of prostate cancer were compared according to the postoperative pathological results. The results showed that the diagnostic rates of each subgroup in the group A were 28.57%, 66.67%, 70% and 91.67%, while the diagnostic rates of each subgroup in the group B were 9.52%, 25.00%, 60.00% and 86.11%, respectively. Compared with the traditional puncture method, MR-TRUS guided puncture significantly improved the diagnostic rate in patients of PSA ≤ 10 µ g/L and 10 < PSA ≤ 20 µ g/h (P<0.05). The diagnostic rate of the two puncture methods was not significantly different in patients of 20 < PSA ≤ 50 µ g/L and PSA > 50 µ g/L (P > 0.05). Compared with the traditional puncture method, the sensitivity and accuracy of MR-TRUS guided puncture were significantly improved (P < 0.05). In summary, patients of PSA ≤ 10 µ g/L and 10 PSA ≤ 20 µ g/L should undergo targeted puncture guided by MRI and ultrasound fusion, which can significantly improve the diagnosis rate of prostate cancer. [ABSTRACT FROM AUTHOR]