Application of Color Doppler Ultrasound Combined with Fibroscan Scoring System in the Diagnosis of Chronic Hepatitis B Fibrosis.

To explore the application value of color Doppler ultrasound combined with Fibroscan scoring system in the diagnosis of chronic hepatitis B fibrosis, a total of 300 patients with chronic hepatitis B undergoing ultrasound-guided liver biopsy were selected, among which 235 patients had liver fibrosis (observation group) and 65 patients didn't have liver fibrosis (control group). The color Doppler ultrasound parameters [including main portal vein diameter (mPVD), splenic vein diameter (SVD), main portal vein blood flow (mPBF), mean velocity of main portal vein (mPVm), portal vein congestion index (CD, mean velocity of splenic vein (sVm), splenic vein blood flow (sVBF)] and liver stiffness measurement (LSM) of two groups were statistically analyzed, as well as the parameters between different liver fibrosis stages. The results showed that the AUC of combined diagnosis of CHB liver fibrosis was the highest, which was 0.876 (P<0.05). SVD, mPVD, CI, LSM were positively correlated with liver fibrosis stage, mPVm was negatively correlated with liver fibrosis stage (P < 0.05). The AUC of liver fibrosis stage diagnosed by LSM was the largest (P < 0.05). It can be seen that using color Doppler ultrasound and FibroScan directional instantaneous elastography system, which detected SVD, mPVD, CI, mPVm, and LSM, can effectively diagnose CHB liver fibrosis. And each parameter is closely related to the degree of liver fibrosis. The combined detection is expected to be a non-invasive method for evaluating liver fibrosis and severity. [ABSTRACT FROM AUTHOR]