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Metallo‐Helicoid with Double Rims: Polymerization Followed by Folding by Intramolecular Coordination.

Authors :
Yin, Guang‐Qiang
Kandapal, Sneha
Liu, Chung‐Hao
Wang, Heng
Huang, Jianxiang
Jiang, Shu‐Ting
Ji, Tan
Yan, Yu
Khalife, Sandra
Zhou, Ruhong
Ye, Libin
Xu, Bingqian
Yang, Hai‐Bo
Nieh, Mu‐Ping
Li, Xiaopeng
Source :
Angewandte Chemie International Edition; 1/18/2021, Vol. 60 Issue 3, p1281-1289, 9p
Publication Year :
2021

Abstract

In this study, we established a feasible strategy to construct a new type of metallo‐polymer with helicoidal structure through the combination of covalent polymerization and intramolecular coordination‐driven self‐assembly. In the design, a tetratopic monomer (M) was prepared with two terminal alkynes in the outer rim for polymerization, and two terpyridines (TPYs) in the inner rim for subsequent folding by selective intramolecular coordination. Then, the linear covalent polymer (P) was synthesized by polymerization of M via Glaser‐Hay homocoupling reaction. Finally, intramolecular coordination interactions between TPYs and Zn(II) folded the backbone of P into a right‐ or left‐handed metallo‐helicoid (H) with double rims. Owing to multiple positive charges on the inner rim of helicoid, double‐stranded DNA molecules (dsDNA) could interact with H through electrostatic interactions. Remarkably, dsDNA allowed exclusive formation of H with right handedness by means of chiral induction. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14337851
Volume :
60
Issue :
3
Database :
Complementary Index
Journal :
Angewandte Chemie International Edition
Publication Type :
Academic Journal
Accession number :
148078474
Full Text :
https://doi.org/10.1002/anie.202010696