Frequent handwashing and disinfection: a potential new trigger for aquagenic wrinkling of the palms caused by COVID‐19 outbreak.

Aquagenic wrinkling of the palms (AWP) is an uncommon reaction causing transient, oedematous, whitish papules and plaques to form on the palms after brief exposure to water.1-3 This condition has been reported under various names, including syringeal acrokeratoderma, aquagenic palmoplantar keratoderma, transient reactive papulotranslucent acrokeratoderma, aquagenic keratoderma and aquagenic papulotranslucent acrokeratoderma. AWP can be diagnosed via a provocation test using water1,2; thus, a compress soaked in 35-37°C water was applied to the patient's hands. Genetic analysis for mutations in the cystic fibrosis transmembrane receptor gene was recommended; however, this was not approved by the patient. [Extracted from the article]