Back to Search
Start Over
Varicella vaccination in Italy and Germany – different routes to success: a systematic review.
- Source :
- Expert Review of Vaccines; Sep2020, Vol. 19 Issue 9, p843-869, 27p
- Publication Year :
- 2020
-
Abstract
- Italy (in pilot regions) and Germany (nationwide) were the first European countries to introduce universal varicella vaccination (UVV) programs. A systematic review was performed to assess varicella epidemiology before UVV programs and the impact of 1-dose and 2-dose UVV programs in Italy and Germany. Italy implemented 1- or 2-dose UVV programs successively in eight pilot regions between 2003 and 2011 and nationwide in 2017. Germany implemented 1- and 2-dose UVV programs in 2004 and 2009, respectively. While Italy had two nationwide surveillance systems in place for varicella in the pre-vaccination era, in Germany, a mandatory notification system for varicella was only introduced in the New Federal States 2 years before the 1-dose UVV implementation. Substantial reductions in moderate/severe varicella and varicella-related hospitalization incidence occurred during the 1-dose era. Further reductions were reported in Italy and Germany after the recommendation of a second dose in a long or short schedule, respectively. Different benefit-risk evaluations of a tetravalent varicella-containing vaccine (MMRV) used as a first dose led to different recommendations (MMRV versus MMR+V) in these countries. Vaccination strategies in both countries tailored to country-specific needs and goals led to a reduction in varicella-related health care hospitalization costs. [ABSTRACT FROM AUTHOR]
- Subjects :
- CHICKENPOX
VACCINATION
MEDICAL care costs
Subjects
Details
- Language :
- English
- ISSN :
- 14760584
- Volume :
- 19
- Issue :
- 9
- Database :
- Complementary Index
- Journal :
- Expert Review of Vaccines
- Publication Type :
- Academic Journal
- Accession number :
- 147042025
- Full Text :
- https://doi.org/10.1080/14760584.2020.1825947