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Preclinical studies: how much can we rely on?

Authors :
Rothstein, Jeffrey
Source :
Amyotrophic Lateral Sclerosis & Other Motor Neuron Disorders; Sep2004 Supplement 1, Vol. 5, p22-25, 4p
Publication Year :
2004

Abstract

Examines the reliability of results from clinical trials in amyotrophic lateral sclerosis therapeutics in the U.S. Basis of modern pre-clinical therapeutics; Limitations of pre-clinical models; Excellence of transgenic rodent models as an excellent tool to reveal potential new human therapies.

Subjects

Subjects :
AMYOTROPHIC lateral sclerosis
MEDICAL research
THERAPEUTICS
CLINICAL medicine

Details

Language :
English
ISSN :
14660822
Volume :
5
Database :
Complementary Index
Journal :
Amyotrophic Lateral Sclerosis & Other Motor Neuron Disorders
Publication Type :
Academic Journal
Accession number :
14664831
Full Text :
https://doi.org/10.1080/17434470410020012
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