Treatment of Intrabony Defect Using Platelet Rich Fibrin Combined with Bioactive Glass: A Case Report of a Maxillary Central Incisor.

The ultimate goal of periodontal therapy is to regenerate the lost periodontal tissues caused by periodontitis. Platelet rich fibrin (PRF), a rich source of autologous growth factors and cytokines, is an upcoming therapeutic approach in the management of periodontal osseous defects. Combination of autologous PRF and the alloplastic bone substitutes holds a promising potential of enhanced bone regeneration. This case report includes the management of an intrabony osseous defect in relation to #21 with a combination of Platelet Rich Fibrin & bioactive glass (calcium phosphosilicatealloplast) with the clinical and radiographic evaluations using cone beam computed tomography (CBCT) for a 9 months follow up period. [ABSTRACT FROM AUTHOR]