ICP-MS Cones: Why, When and How to Maintain.

The article discusses the proper maintenance and conditioning of inductively coupled plasma-mass spectrometry (ICP-MS) interface cones. Topics include the importance of following the recommended maintenance guidelines of the instrument manufacturer, the adverse effects of operating ICP-MS with cones in poor condition like loss of sensitivity, unreliable data, and increased background signal, as well as the dilute Citranox solution as cleaning agent.