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Poly‐L‐lactide scaffolds with super pores obtained by freeze‐extraction method.
- Source :
- Journal of Biomedical Materials Research, Part B: Applied Biomaterials; Nov2020, Vol. 108 Issue 8, p3162-3173, 12p
- Publication Year :
- 2020
-
Abstract
- A nonplanar polylactide scaffold to be used in tissue engineering was obtained by freeze‐extraction method. Properties of the scaffold were modified by adding Eudragit® E100. The impact of the modification on morphology, porosity and pore size, mass absorbability, mechanical properties was determined. Scanning electron microscopy (SEM), hydrostatic weighing test, static compression test was used to this end. The chemical composition of the scaffold was defined based on infrared spectroscopy (FTIR) and energy‐dispersive X‐ray spectroscopy (EDX). Biocompatibility was confirmed by quantitative tests and microscopic observation. The obtained results show that the obtained scaffolds may be applied as a carrier of hydrophilic cellular growth factors for more efficient tissue regeneration. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15524973
- Volume :
- 108
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- Journal of Biomedical Materials Research, Part B: Applied Biomaterials
- Publication Type :
- Academic Journal
- Accession number :
- 146250949
- Full Text :
- https://doi.org/10.1002/jbm.b.34642