The fentanyls: pharmacological and clinical aspects relevant to Australia.

<bold>Objective: </bold>North American and other jurisdictions have seen an alarming rise in the abuse of the fentanyls, with related overdose deaths. We sought to review this group of drugs to alert Australian psychiatrists and drug and alcohol clinicians to their clinical effects and potential harms.<bold>Conclusions: </bold>The extreme potency of the fentanyls underlie their lethality. Vigilance and investment from both policy makers and health care providers are required to mitigate harm from a possible future Australian fentanyl epidemic. [ABSTRACT FROM AUTHOR]