Comparison of wavefront aberrations in eyes with multifocal and monofocal iols before and after Nd:YAG laser capsulotomy for posterior capsule opacification.

Purpose: The aim of this study was to compare wavefront aberrations before and after Nd:YAG capsulotomy in multifocal intraocular lens (MfIOL) and monofocal (MoIOL) pseudophakic eyes with posterior capsule opacification (PCO). Materials and methods: Wavefront aberrations were measured using a ARK-10000 topographer before and after Nd:YAG capsulotomy in eyes that underwent MfIOL or MoIOL implantation and developed PCO. Total and higher-order aberrations (HOAs) values were evaluated as root mean square (RMS). Results: The study included 64 eyes with MfIOLs (64 patients) and 72 with MoIOLs (72 patients) that developed PCO. Total RMS values before and 1 month after Nd:YAG capsulotomy were 0.863 ± 0.27 and 0.504 ± 0.24 in the MFIOL group and 0.862 ± 0.31 and 0.466 ± 0.26 in the MoIOL group, respectively. Total RMS values did not differ significantly between the groups before (p = 0.914) or 1 month after Nd:YAG laser capsulotomy (p = 0.357), but decreased significantly after Nd:YAG capsulotomy compared to baseline in both the MfIOL (p = 0.027) and MoIOL (p = 0.012) groups. HOA values before and 1 month after Nd:YAG capsulotomy were 0.546 ± 0.23 and 0.364 ± 0.19 in the MfIOL group and 0.500 ± 0.21 and 0.346 ± 0.18 in the MoIOL group, respectively. HOA values did not differ significantly before (p = 0.828) or after Nd:YAG capsulotomy (p = 0.111), while both groups showed significant reduction in HOAs after Nd:YAG capsulotomy (MfIOL: p = 0.021, MoIOL: p = 0.027). Conclusions: Nd:YAG capsulotomy reduces total and HOAs to the same extent in eyes with both MfIOLs and MoIOLs, with no significant impact of the IOL design. [ABSTRACT FROM AUTHOR]