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Invasive Mold Infections After Chimeric Antigen Receptor–Modified T-Cell Therapy: A Case Series, Review of the Literature, and Implications for Prophylaxis.
- Source :
- Clinical Infectious Diseases; 8/1/2020, Vol. 71 Issue 3, p672-676, 5p
- Publication Year :
- 2020
-
Abstract
- Data on invasive mold infections (IMIs) after chimeric antigen receptor-modified T-cell (CAR-T-cell) therapy are limited. We describe 2 patients with post–CAR-T-cell IMI (Fusarium, Mucorales) and review the published literature. We propose strategies to prevent IMIs in patients, based on the IMI rate and presence of neutropenia or steroid use. [ABSTRACT FROM AUTHOR]
- Subjects :
- IMMUNOTHERAPY
LEUKEMIA
MYCOSES
NEUTROPENIA
RISK assessment
DISEASE risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 10584838
- Volume :
- 71
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Clinical Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 144824381
- Full Text :
- https://doi.org/10.1093/cid/ciz1127