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Invasive Mold Infections After Chimeric Antigen Receptor–Modified T-Cell Therapy: A Case Series, Review of the Literature, and Implications for Prophylaxis.

Authors :
Haidar, Ghady
Dorritie, Kathleen
Farah, Rafic
Bogdanovich, Tatiana
Nguyen, M Hong
Samanta, Palash
Source :
Clinical Infectious Diseases; 8/1/2020, Vol. 71 Issue 3, p672-676, 5p
Publication Year :
2020

Abstract

Data on invasive mold infections (IMIs) after chimeric antigen receptor-modified T-cell (CAR-T-cell) therapy are limited. We describe 2 patients with post–CAR-T-cell IMI (Fusarium, Mucorales) and review the published literature. We propose strategies to prevent IMIs in patients, based on the IMI rate and presence of neutropenia or steroid use. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10584838
Volume :
71
Issue :
3
Database :
Complementary Index
Journal :
Clinical Infectious Diseases
Publication Type :
Academic Journal
Accession number :
144824381
Full Text :
https://doi.org/10.1093/cid/ciz1127