A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells.

Authors :: Feng, Ling
Xie, Yusheng
Au-Yeung, Sung King
Hailu, Hagos Birhanu
Liu, Zhiyang
Chen, Qingxin
Zhang, Jie
Pang, Qiuxiang
Yao, Xi
Yang, Mengsu
Zhang, Liang
Sun, Hongyan
Source :: Chemical Communications; 8/4/2020, Vol. 56 Issue 60, p8480-8483, 4p
Publication Year :: 2020
Abstract: A rotor-based probe MRMP-1 was designed and synthesized. MRMP-1 can bind to plasma membranes very quickly and stably with remarkable fluorescence enhancement. It can be used to monitor the dynamic changes in cell membranes in real-time under stimuli conditions. Importantly, MRMP-1 is the first rotor-based fluorescent sensor to label exosomes in living cells. [ABSTRACT FROM AUTHOR]

Subjects :: CELL membranes
FLUORESCENT probes
MOLECULAR probes
CELLS
EXOSOMES
FLUORESCENCE

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