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Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium.
- Source :
- American Journal of Respiratory & Critical Care Medicine; 7/15/2020, Vol. 202 Issue 2, pE1-E20, 20p
- Publication Year :
- 2020
-
Abstract
- The article presents a study related to the expression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) angiotensin converting enzyme (ACE2) receptor in the human airway epithelium. It mentions ACE2 is expressed similarly in trachea and large airway epithelia (LAE), with lower expression in the small airway epithelia (SAE); and levels of miR-1246 expression could play a role in ACE2 upregulation in SAE of smokers; and Covid-19 fusion is affected by activity of an enzyme.
- Subjects :
- SARS-CoV-2
ANGIOTENSIN converting enzyme
EPITHELIUM
CIGARETTE smokers
COVID-19
Subjects
Details
- Language :
- English
- ISSN :
- 1073449X
- Volume :
- 202
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- American Journal of Respiratory & Critical Care Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 144647565
- Full Text :
- https://doi.org/10.1164/rccm.202003-0541oc