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Sorption of 89Zr on hydroxyapatite nanoparticles as carriers for nuclear medicine.

Authors :
Kazakov, Andrey G.
Severin, Alexander V.
Source :
Journal of Radioanalytical & Nuclear Chemistry; Jul2020, Vol. 325 Issue 1, p199-205, 7p, 1 Diagram, 6 Graphs
Publication Year :
2020

Abstract

The sorption behavior of <superscript>89</superscript>Zr on hydroxyapatite (Ca<subscript>10</subscript>(PO<subscript>4</subscript>)<subscript>5</subscript>(OH)<subscript>2</subscript>, HA) nanoparticles in an aqueous medium and 0.9% NaCl at various pH values was studied. The fast kinetics of the process was determined; the stability of the obtained conjugate in a model biological medium at 25 and 37 °C was shown. The possibility of further use of the <superscript>89</superscript>Zr@HA conjugate in various radiopharmaceuticals is discussed. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
02365731
Volume :
325
Issue :
1
Database :
Complementary Index
Journal :
Journal of Radioanalytical & Nuclear Chemistry
Publication Type :
Academic Journal
Accession number :
144220222
Full Text :
https://doi.org/10.1007/s10967-020-07192-8