Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis.

To the Editor, Atopic dermatitis (AD) is a prevalent inflammatory skin disease. The I FLG- i stratified analyses showed a trend toward cat exposure being a risk factor in children with I FLG i mutations and a protective factor in children without I FLG i mutations (Figure and Table S3). GLO:1X5/01jun20:all14162-fig-0001.jpg PHOTO (COLOR): Interaction between cat exposure and common FLG mutations in relation to (A) early-onset atopic dermatitis, (B) current atopic dermatitis, and (C) atopic dermatitis in the first 7 y of life gl We found no interaction between cat exposure in infancy and mutations in I FLG i on "early-onset AD" or "AD ever.". [Extracted from the article]