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Association of T. gondii infection with suicide: a systematic review and meta-analysis.

Authors :
Soleymani, Eissa
Faizi, Fariba
Heidarimoghadam, Rashid
Davoodi, Lotfollah
Mohammadi, Younes
Source :
BMC Public Health; 5/24/2020, Vol. 20 Issue 1, p1-7, 7p, 1 Diagram, 1 Chart, 1 Graph
Publication Year :
2020

Abstract

<bold>Background: </bold>Findings on the association between Toxoplasma gondii (T. gondii) infection and suicide are contradictory. This paper aimed to resolve this uncertainty by conducting a meta-analysis.<bold>Methods: </bold>We found the relevant studies using keywords include "Toxoplasmosis" and "Suicide" and the related synonyms in international databases such as ISI, Medline, and Scopus. The eligible studies were included in the meta-analysis phase. The random effect approach was applied to combine the results.<bold>Results: </bold>Out Of 150 initial studies, 15 were included in the meta-analysis. Odds of suicide in people with T. gondii infection was 43% (OR: 1.43, 95%CI; 1.15 to 1.78) higher than those without this infection. The test for publication bias was not statistically significant, which indicates the absence of likely publication bias.<bold>Conclusion: </bold>This study confirms that T. gondii infection is a potential risk factor for suicide. To reduce cases of suicide attributable to T. gondii infection, it is recommended to implement some measures to prevent and control the transmission of the disease. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14712458
Volume :
20
Issue :
1
Database :
Complementary Index
Journal :
BMC Public Health
Publication Type :
Academic Journal
Accession number :
143395899
Full Text :
https://doi.org/10.1186/s12889-020-08898-w