Comparative Study between Magnesium Sulfate and Pethidine for Controlling Shivering after Spinal Anesthesia.

Background: Shivering is an involuntary muscular activity. Increased muscle tone during shivering is due to temperatureinduced changes in neuronal activity in the reticular formation. Synchronization of motor neurons during shivering may be mediated by recurrent inhibition through renshaw cells. Aim of the Work: To verify the efficacy of magnesium sulfate for controlling post spinal shivering, to compare the efficacy of magnesiumsulfate and pethidine for controlling post spinal shivering and to detect the side effects of both magnesium sulfate and pethidine after their use for controlling post spinal shivering. Patients and Methods: This prospective study was conducted at El-Matarya Teaching Hospital from 2018 till 2019. After obtaining approval from the Research Ethical Committee of Ain Shams University, informed patient consent was obtained before the procedure. After giving the spinal anesthesia, only patients who developed post-spinal shivering were followed for the study. 60 patients with post-spinal shivering were included with the following criteria: Results: Regarding age, weight, height and duration of surgery; there were no statistically significant differences between the two studied groups. Comparison of the two studied groups revealed no statistically significant changes at all times of measurement. Conclusion: Magnesium sulfate in a dose of 30 mg/kg IV infusion in 100 ml normal saline over 10 min is effective for control of post spinal shivering. Pethidine in a dose of 0.5 mg/kg IV bolus is effective for control of post spinal shivering. [ABSTRACT FROM AUTHOR]