Kindler Syndrome: Report of Two Cases and Review of the Literature.

We evaluated two patients with hereditary bullous polkiloderma. Both tiad acral bullae, generalized poikiloderma with prominent atrophy, and acral keratoses. One patient, with sporadic disease, had, in addition, urethrai and subglottic stenoses, webbing of digits, and poor dentition. Hie other patient, whose disease was dominantly inherited, had koilonychia. The results of cutaneous histopathology, electron microscopy, and immunofluorescence mapping studies are presented, it is possibie that Kindler syndrome and Weary's hereditary acrokeratotic poikiloderma are variants of the same disease. [ABSTRACT FROM AUTHOR]