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Association between dyslipidemia and blood lipids concentration with smoking habits in the Kurdish population of Iran.

Authors :
Moradinazar, Mehdi
Pasdar, Yahya
Najafi, Farid
Shahsavari, Soodeh
Shakiba, Ebrahim
Hamzeh, Behrooz
Fakhri, Negin
Source :
BMC Public Health; 5/13/2020, Vol. 20 Issue 1, p1-10, 10p, 2 Diagrams, 2 Charts
Publication Year :
2020

Abstract

<bold>Background: </bold>Smoking is the most preventable cause of most chronic diseases such as cardiovascular disease (CVD). Dyslipidemia is also an important risk factor for CVD. Yet, research has provided contradicting findings regarding the association between smoking and blood lipids. This paper examines the relationship between dyslipidemia and smoking based on the results of a cross-sectional sample of a Kurdish population in western Iran.<bold>Methods: </bold>This population-based study was derived from the recruitment phase of Ravansar Non-Communicable Disease (RaNCD) cohort study. Logistic regression model adjusted by confounding variables was used to determine the relationship between smoking and blood lipid components. In addition, dose-response relationship between blood lipids and the number of smoked cigarettes was evaluated.<bold>Results: </bold>For the purpose of this study, 7586 participants were examined. The lifetime prevalence of smoking was 19.9%, and 11.8% were current smokers. The prevalence of dyslipidemia in current smokers (54.9%) was higher than former smokers (43.9%) and in turn former smokers higher than non-smokers (38.0%). Current smokers had greater risk of abnormal HDL cholesterol [OR (95% CI), 2.28(1.98 -2.62)] and triglyceride [OR (95% CI), 1.37(1.15 -1.67)] compared to non-smokers. There was no significant difference in total cholesterol and LDL cholesterol between the two groups. A dose-response relationship was found between the number of cigarettes smoked and HDL-C and TG but no relationship was observed in terms of total cholesterol and LDL-C.<bold>Conclusions: </bold>As compared to non-smokers, current smokers and former smokers had abnormal HDL-C and triglyceride and abnormal total cholesterol and triglyceride, respectively. After quitting smoking, heavy smokers showed a more normal HDL-C and total cholesterol levels than the people who tended to smoke a lower number of cigarettes per day. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14712458
Volume :
20
Issue :
1
Database :
Complementary Index
Journal :
BMC Public Health
Publication Type :
Academic Journal
Accession number :
143193179
Full Text :
https://doi.org/10.1186/s12889-020-08809-z