Relationships of Lipids Profile with Health-Related Quality of Life in Chinese Centenarians.

Objectives: With the acceleration of the process of aging population, to enjoy a higher health-related quality of life (HRQoL) is the goal of the elderly population and public health. Studies on relationship between HRQoL and lipid profile through a large sample of representative elderly population are scare. Objective: This study was conducted to firstly explore the relationships of lipid profile with HRQoL in Chinese centenarian population. Participants: A complete sample of 1002 participants aged over 100 years from Hainan province were recruited in the current study. Main measure: Questionnaire investigation, physical examination and blood specimen collection were carried out by family survey. The EuroQol-5 Dimensions(EQ-5D, and EQ-VAS were used to assess HRQoL. Results: In multivariate linear regression analyses, a significant association was found between EQ-5D and lipid profile, including total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and similar association was also existed between EQ-VAS and TC, LDL-C HDL-C, after adjustment. The score of EQ-5D and EQ-VAS in male centenarian was higher than that of the female centenarian. Conclusion: Lipid profile was positively associated with the HRQoL in Chinese centenarians. [ABSTRACT FROM AUTHOR]