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Fulminant Acanthamoeba castellanii Encephalitis in an Ibrutinib-Treated Patient.

Authors :
Crothers, Jessica W
Hsu, Liangge
Marty, Francisco M
Source :
Open Forum Infectious Diseases; Feb2020, Vol. 7 Issue 2, pN.PAG-N.PAG, 1p
Publication Year :
2020

Abstract

We report a case of fulminant Acanthamoeba castellanii encephalitis in a patient with chronic lymphocytic leukemia treated with ibrutinib. The unusually rapid neurologic decline and fatal outcome observed are probably related to alterations in immunologic function associated with inhibition of Bruton tyrosine kinase. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
23288957
Volume :
7
Issue :
2
Database :
Complementary Index
Journal :
Open Forum Infectious Diseases
Publication Type :
Academic Journal
Accession number :
142475651
Full Text :
https://doi.org/10.1093/ofid/ofaa025