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Kalshiolin A, new lignan from Kalimeris shimadai.
- Source :
- Journal of Asian Natural Products Research; May2020, Vol. 22 Issue 5, p489-495, 7p
- Publication Year :
- 2020
-
Abstract
- The Asian plant Kalimeris shimadai has been used as food and ethnologic medicine for over a thousand years. In this study, we isolated and identified one new lignan, kalshiolin A (1), and 12 known lignans (2–13). The structures were characterized by the comprehensive analyses of spectroscopic data (HR-ESI-MS, IR, 1D, and 2D-NMR) and the absolute configuration of 1 was determined from ECD calculations. The new compound 1 was also screened for cytotoxic activity but did not show significant potency (IC<subscript>50</subscript> 35.9–43.3 μM) against A549, MDA-MB-231, MCF7, KB, and KB-VIN cell lines. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10286020
- Volume :
- 22
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Journal of Asian Natural Products Research
- Publication Type :
- Academic Journal
- Accession number :
- 142336477
- Full Text :
- https://doi.org/10.1080/10286020.2019.1592164