Back to Search
Start Over
Clinical Diagnostic Testing for Human Cytomegalovirus Infections.
- Source :
- Journal of Infectious Diseases; 2020 Supplement, Vol. 221, pS74-S85, 12p
- Publication Year :
- 2020
-
Abstract
- Human cytomegalovirus (HCMV) infections are among the most common complications arising in transplant patients, elevating the risk of various complications including loss of graft and death. HCMV infections are also responsible for more congenital infections worldwide than any other agent. Congenital HCMV (cCMV) infections are the leading nongenetic cause of sensorineural hearing loss and a source of significant neurological disabilities in children. While there is overlap in the clinical and laboratory approaches to diagnosis of HCMV infections in these settings, the management, follow-up, treatment, and diagnostic strategies differ considerably. As yet, no country has implemented a universal screening program for cCMV. Here, we summarize the issues, limitations, and application of diagnostic strategies for transplant recipients and congenital infection, including examples of screening programs for congenital HCMV that have been implemented at several centers in Japan, Italy, and the United States. [ABSTRACT FROM AUTHOR]
- Subjects :
- HUMAN cytomegalovirus diseases
DIAGNOSIS methods
HUMAN cytomegalovirus
CHILDREN with disabilities
KIDNEY transplant complications
COMMUNICABLE disease diagnosis
CYTOMEGALOVIRUS disease diagnosis
CYTOMEGALOVIRUSES
NEWBORN screening
MOLECULAR diagnosis
COMMUNICABLE diseases
PRENATAL diagnosis
CYTOMEGALOVIRUS diseases
PREGNANCY complications
ROUTINE diagnostic tests
VERTICAL transmission (Communicable diseases)
DISEASE management
TRANSPLANTATION of organs, tissues, etc.
ALGORITHMS
INFECTIOUS disease transmission
Subjects
Details
- Language :
- English
- ISSN :
- 00221899
- Volume :
- 221
- Database :
- Complementary Index
- Journal :
- Journal of Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 142190200
- Full Text :
- https://doi.org/10.1093/infdis/jiz601