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Clinicopathological Analysis of 90 Cases of Polyacrylamide Hydrogel Injection for Breast Augmentation Including 2 Cases Followed by Breast Cancer.

Authors :
Yang, Ying
Li, Shumo
He, Jia
Zhao, Xian
Chen, Wei
Dai, Xiaoming
Liu, Liu
Source :
Breast Care; 2020, Vol. 15 Issue 1, p38-44, 7p, 2 Color Photographs, 1 Black and White Photograph, 1 Chart
Publication Year :
2020

Abstract

Background: Although polyacrylamide hydrogel (PAAG) injection for breast augmentation has been prohibited for many years, the long-term complications will be significant for a long period. Few research articles have focused on the clinicopathological analysis. Materials and Methods: We summarized clinical and pathological features of 90 cases after PAAG-injected breast augmentation, including 2 cases of breast cancer developed following PAAG injection. Results: All patients were females between the ages of 30 and 64 years (mean, 44 years). The complications included masses (75.58%), pain (45.35%), migration (22.09%), deformation (18.60%), infection (16.28%), induration (4.65%), and psychological fear (2.33%). Microscopically, the PAAG presented as purple gel pools, and the foreign body reaction was noted in all 90 patients. The proportion of fibrous component exceeded 90% in 26 cases (28.89%). Chronic and acute inflammation was noted in 70 (77.78%) and 9 (10%) patients, respectively. The mammary gland around the gel displayed atrophy in 18 cases (20.00%), adenosis in 33 cases (36.67%), ductal carcinoma in situ in 1 case (1.11%), and invasive carcinoma in 1 case (1.11%). Conclusion: The long-term complications of PAAG-injected breast augmentation are various and complex. Pathologically, these complications are associated with foreign body reaction, fibrosis, and inflammation. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16613791
Volume :
15
Issue :
1
Database :
Complementary Index
Journal :
Breast Care
Publication Type :
Academic Journal
Accession number :
141822876
Full Text :
https://doi.org/10.1159/000499832