A new amplification strategy for a quartz crystal microbalance miRNA sensor based on selective interactions between a metal–organic framework and miRNA.

A new strategy of using a MOF as an effective amplifier in a QCM miRNA sensor was presented based on the selective interaction between a MOF (UiO-66) with different zeta potentials and different miRNAs. The signal can be significantly enhanced, which leads to significantly improved performance in miRNA detection. [ABSTRACT FROM AUTHOR]