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A luminescent MOF as a fluorescent sensor for the sequential detection of Al3+ and phenylpyruvic acid.
- Source :
- New Journal of Chemistry; 1/28/2020, Vol. 44 Issue 4, p1307-1312, 6p
- Publication Year :
- 2020
-
Abstract
- Aluminum is a widely distributed element with potential harm to human health, and the analysis of phenylpyruvic acid (PPA) is also routine in clinical uroscopy for metabolic disorders. In this work, we synthesized a UiO-66-backboned MOF, UiO-66-(OH)<subscript>2</subscript>, to construct an "off–on–off" platform for the sequential fluorescence detection of Al<superscript>3+</superscript> and PPA. With incorporated hydroxyl groups, this MOF could capture Al<superscript>3+</superscript> ions in aqueous solution and show enhanced fluorescence response through an excited-state intramolecular proton transfer mechanism. The binding affinity of PPA to Al<superscript>3+</superscript> is stronger than that to the MOF; therefore, the further addition of this compound to UiO-66-(OH)<subscript>2</subscript>–Al<superscript>3+</superscript> extracts the adsorbed Al<superscript>3+</superscript> and restores the original weak emission of the MOF. UiO-66-(OH)<subscript>2</subscript> exhibited good selectivity and sensitivity (DL = 47 nM for Al<superscript>3+</superscript> and 100 nM for PPA) in both steps of detection and was successfully applied to the analysis of PPA in artificial urine. [ABSTRACT FROM AUTHOR]
- Subjects :
- HYDROXYL group
ACID analysis
AQUEOUS solutions
ION traps
METABOLIC disorders
Subjects
Details
- Language :
- English
- ISSN :
- 11440546
- Volume :
- 44
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- New Journal of Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 141412478
- Full Text :
- https://doi.org/10.1039/c9nj05439a