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Treatment of severe hypertension during pregnancy: we still do not know what the best option is.

Authors :
Wertaschnigg, Dagmar
Wang, Rui
Reddy, Maya
Costa, Fabricio Da Silva
Mol, Ben Willem J.
Rolnik, Daniel L.
Source :
Hypertension in Pregnancy; Feb2020, Vol. 39 Issue 1, p25-32, 8p, 3 Charts
Publication Year :
2020

Abstract

Intracranial hemorrhage and stroke are primary causes of maternal mortality in pregnancies affected by hypertensive disorders. As such antihypertensive therapy plays a crucial role in the management of severe hypertension. However, the target level to achieve the best outcome for both - mother and fetus - is still unclear. Moreover, given the lack of well-designed randomized controlled trials with standardized key outcomes, the current choice of antihypertensive medications depends rather on clinicians' preference. Furthermore, data on long-term outcomes of offspring is not available. Therefore, there is an urgent need for randomized trials comparing different anti-hypertensive options to address efficacy and safety questions. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10641955
Volume :
39
Issue :
1
Database :
Complementary Index
Journal :
Hypertension in Pregnancy
Publication Type :
Academic Journal
Accession number :
141412328
Full Text :
https://doi.org/10.1080/10641955.2019.1708383