Back to Search
Start Over
Aggregation-based determination of mercury(II) using DNA-modified single gold nanoparticle, T-Hg(II)-T interaction, and single-particle ICP-MS.
- Source :
- Microchimica Acta; Jan2020, Vol. 187 Issue 1, p1-10, 10p
- Publication Year :
- 2020
-
Abstract
- An ultrasensitive assay is described for the detection and determination of Hg<superscript>2+</superscript>(aq) in water samples based on single-particle inductively-coupled plasma/mass spectrometry (spICP-MS). In the presence of Hg<superscript>2+</superscript>(aq), AuNPs modified with a segment of single-stranded DNA aggregate due to the formation of the well-known thymine (T)-Hg<superscript>2+</superscript>-T complex. Single particle (sp) ICP-MS is used quantify the degree of aggregation by the overall decrease in number of detected AuNPs or NP aggregates. Compared with most other Hg<superscript>2+</superscript> assays that use the same principle of aggregation-dispersion with DNA modified AuNPs, this method has a much lower detection limit of (0.031 ng L<superscript>−1</superscript>, 155 fM) and a wider (10,000-fold) linear range (up to 1 μg L<superscript>−1</superscript>). The method also showed good practical potential because of its minimal interference from the water sample matrix. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00263672
- Volume :
- 187
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Microchimica Acta
- Publication Type :
- Academic Journal
- Accession number :
- 141277918
- Full Text :
- https://doi.org/10.1007/s00604-019-4057-6