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Polyphenols contents, heavy metals analysis and in vitro antibacterial activity of extracts from Cladanthus arabicus and Bubonium imbricatum of Moroccan Origin.

Authors :
Aghraz, Abdellah
Albergamo, Ambrogina
Benameur, Qada
Salvo, Andrea
Larhsini, Mustapha
Markouk, Mohamed
Gervasi, Teresa
Cicero, Nicola
Source :
Natural Product Research; Jan2020, Vol. 34 Issue 1, p63-70, 8p
Publication Year :
2020

Abstract

Aim of this study was to evaluate polyphenols and major and trace elements of Cladanthus arabicus and Bubonium imbricatum, along with their in vitro antibacterial activity against six multidrug resistant Enterobacteriaceae (Escherichia coli S33/16, E. coli S34/16, Proteus mirabilis S32/16, Klebsiella pneumoniae S12/16, Enterobacter cloacae S5/16, and Salmonella sp S12/14). UV spectrophotometry, ultra-high-performance liquid chromatography coupled to mass spectrometry and inductively coupled plasma mass spectrometry were used to evaluate total polyphenol content, quali-quantitative profile of single polyphenols and inorganic elements of the extract. The antibacterial activity was investigated by standard methods. Twelve polyphenols were identified in both plants and these were more concentrated in B. imbricatum than C. arabicus extracts. High levels of minerals, essential trace elements and tolerable levels of heavy metals (Cd, As and Pb) were found. Furthermore, the extracts showed also a strong in vitro antibacterial activity, particularly versus E. coli S33/16 (MIC, 0.125 mg ml<superscript>−1</superscript>). [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14786419
Volume :
34
Issue :
1
Database :
Complementary Index
Journal :
Natural Product Research
Publication Type :
Academic Journal
Accession number :
140974171
Full Text :
https://doi.org/10.1080/14786419.2019.1573424