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Gender differences in response to sertraline pharmacotherapy in Type A alcohol dependence.
- Source :
- American Journal on Addictions; May/Jun2004, Vol. 13 Issue 3, p236-247, 12p, 3 Charts
- Publication Year :
- 2004
-
Abstract
- We previously established that Babor Type A "lower-risk/severity" alcoholics (n = 55) had better treatment response to fourteen weeks of sertraline (200 mg/day) than placebo, a finding not present for Type B "higher-risk/severity" alcoholics (n = 45). This exploratory study extended these results by examining the original sample for gender differences in response to sertraline pharmacotherapy. Type A alcoholic men, but not Type A alcoholic women, had consistently better outcomes with sertraline compared to placebo on several common drinking measures: time to relapse, days drinking, days drinking heavily, drinks per drinking day, and number of those continually abstinent. There were no significant differences in drinking with sertraline compared to placebo in Type B alcoholic men or women. [ABSTRACT FROM AUTHOR]
- Subjects :
- PEOPLE with alcoholism
SEX differences (Biology)
ANTIDEPRESSANTS
DRUG therapy
THERAPEUTICS
ALCOHOLISM
CLINICAL trials
COMPARATIVE studies
ALCOHOL drinking
RESEARCH methodology
MEDICAL cooperation
ORAL drug administration
PLACEBOS
RESEARCH
SEROTONIN uptake inhibitors
SERTRALINE
SEX distribution
DISEASE relapse
EVALUATION research
RANDOMIZED controlled trials
TREATMENT effectiveness
SEVERITY of illness index
PHARMACODYNAMICS
Subjects
Details
- Language :
- English
- ISSN :
- 10550496
- Volume :
- 13
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- American Journal on Addictions
- Publication Type :
- Academic Journal
- Accession number :
- 14084892
- Full Text :
- https://doi.org/10.1080/10550490490459906