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Comparison of balance outcomes according to treatment modality of vestibular schwannoma.
- Source :
- Laryngoscope; Jan2020, Vol. 130 Issue 1, p178-189, 12p
- Publication Year :
- 2020
-
Abstract
- <bold>Objectives: </bold>We sought to compare balance outcomes according to treatment modality of vestibular schwannoma (VS) via a meta-analysis that divided measuring tools of balance outcomes into three categories based on type.<bold>Methods: </bold>A comprehensive review of the literature from January 1966 to September 2017 was performed, looking for studies about long-term balance outcomes after microsurgery (MS), radiotherapy (RT), or observation for VS. A comprehensive meta-analysis was used to analyze effect sizes, explore possible causes of heterogeneity, and check publication bias with a funnel plot and Egger's regression.<bold>Results: </bold>Among 633 references, 34 were included in the meta-analysis. Perceived dizziness improvement rate was significantly higher in the MS group than in the RT group (odds ratio [OR]: 1.61; 95% confidence interval [CI]: 1.08 to 2.40; P < .05, I2 = 4.18], but no significant difference was observed between the two groups with regard to validated dizziness questionnaire score (standardized mean difference: 0.04; 95% CI: -0.36 to 0.44; P = .84, I2 = 69.61) or dizziness or disequilibrium-related symptom incidence rate (OR: 0.91; 95% CI: 0.50 to 1.68; P = .77, I2 = 0). In a subanalysis conducted within the groups after intervention, the MS group demonstrated a lower vertigo incidence rate (P < .001), and the RT group experienced a significant reduction in validated dizziness questionnaire score (P < .05).<bold>Conclusions: </bold>Our results indicate that MS should be considered at least equal to RT in regard to resolving long-term dizziness and improving balance outcomes. Furthermore, well-designed studies are necessary to predict balance outcomes after VS treatment and to choose from among possible treatment options.<bold>Level Of Evidence: </bold>2a Laryngoscope, 130:178-189, 2020. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0023852X
- Volume :
- 130
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Laryngoscope
- Publication Type :
- Academic Journal
- Accession number :
- 140392075
- Full Text :
- https://doi.org/10.1002/lary.27830